Evaluation of the exposure, dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to TiO2, chrysotile, crocidolite or amosite asbestos in a 90-day quantitative inhalation toxicology study
The study related to chrysotile-containing brake dust has provided two interim results including experimental design, aerosol exposure, lung burdens and BAL in rats and histopathological examination, confocal microscopy and collagen quantification of the lung and pleural cavity with life-time post-exposure observation.